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Valproic Acid, sodium salt

Aliases: Sodium valproate, 2-Propylpentanoic acid Na
商品コード: 14021 Format: 5 g ¥8,000 Buy Now
Application: Histone Acetylation (HAT & HDAC)

for Valproic Acid, sodium saltChemical Properties

MW = 166.2
C8H15O2Na
CAS 1069-66-5
>98% (TLC); NMR (Conforms)

for Valproic Acid, sodium saltDescription

Histone deacetylase inhibitor (IC50 = 400 µM). Demonstrates neuroprotective, anti-cancer and anti-inflammatory activity. Inhibits Aβ production and neuritic plaque formation in Alzheimer's mouse models. Clinically useful anti-convulsant.

for Valproic Acid, sodium saltContents

White powder. May be dissolved in water (50 mg/ml).

for Valproic Acid, sodium saltStorage Conditions

Store desiccated as supplied at 4°C for up to 2 years. Store solutions at -20°C for up to 3 months.

for Valproic Acid, sodium saltReferences

1. CJ Phiel et al. J. Biol. Chem. 2001 276:36734
2. HJ Kim et al. J. Pharmacol. Exp. Ther. 2007, 321:892
3. H Qing et al. J. Exp. Med. 2008, 205:2781

 
Chemical structure of valproic acid, sodium salt.

Chemical structure of Valproic Acid, sodium salt.

 

Technical Data Sheet

Valproic Acid, sodium salt
 

Data Thumbnails

Chemical structure of valproic acid, sodium salt.

Chemical structure of Valproic Acid, sodium salt.
(Click image to enlarge.)