Active Motif,
Tools to analyze nuclear function,
Your CartYour Cart 0 items

Recombinant RXR-α protein

Aliases: NR2B1
商品コード: 31133 Format: 10 µg ¥73,000 Buy Now
Expressed In: E. coli Protein Species: Human

Request a quote for a bulk orderBulk Order Button


for Recombinant RXR-a proteinContents

10 µg of Recombinant RXR-α protein and Dilution Buffer AM1 (20 mM Tris-Cl (pH 8), 20% glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA). Please refer to product insert upon arrival for lot-specific concentration.

for Recombinant RXR-a proteinBackground

RXR-α (Retinoid X Receptor alpha, NR2B1) is a nuclear receptor that mediates the biological effects of retinoids by its involvement in retinoic acid-mediated gene activation. RXR-α exerts its action by binding, as a homodimer or a heterodimer, to specific sequences in the promoters of target genes and regulating their transcription. RXR-α is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.

for Recombinant RXR-a proteinApplication Notes

Recombinant RXR-α is suitable for in vitro transcription, chromatin remodeling and protein-protein interaction assays. 20 ng is sufficient for DNA-protein assays, 20-100 ng is sufficient for reconstituted transcription assays and 100 ng is sufficient for protein-protein interaction studies. The molecular weight of the protein is ~48 kDa. NOTE: The presence of Poly [d(I-C)] in buffers may affect protein functionality and should be avoided.

for Recombinant RXR-a proteinProtein Details

Recombinant RXR-α is isolated from an E. coli strain that carries the coding sequence of the human RXR-α under the control of a T7 promoter (accession number NM 002957). The purified recombinant protein has an N-terminal His-Tag and is greater than 95% homogeneous and contains no detectable protease, DNase and RNase activity.

for Recombinant RXR-a proteinGuarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

 

Technical Data Sheet

Recombinant RXR-α protein