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Recombinant KDM6C protein

Aliases: Histone demethylase UTY,
商品コード: 31575 Format: 10 µg ¥73,000 Buy Now
Expressed In: Baculovirus Protein Species: Human

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for Recombinant KDM6C proteinContents

Recombinant KDM6C protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 5% glycerol, 0.04% Triton X-100, 0.2 mM TCEP. Please refer to product insert upon arrival for lot-specific concentration.

for Recombinant KDM6C proteinBackground

KDM6C (lysine (K)-specific demethylase 6C), also known as UTY (Ubiquitously Transcribed Tetratricopeptide Repeat Containing, Y-Linked) is a KDM6 subfamily member that catalyzes demethylation of N-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression. The activity of UTY (KDM6C) is much weaker than KDM6A and KDM6B, due to point substitutions involved in substrate binding.

for Recombinant KDM6C proteinApplication Notes

Recombinant KDM6C is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.

for Recombinant KDM6C proteinProtein Details

Recombinant KDM6C (accession number NP_009056.3) was expressed in Sf9 cells as full length protein and contains an N-terminal FLAG-Tag with an observed molecular weight of 152.9 kDa. The recombinant protein is >70% pure by SDS-PAGE.

 
Recombinant KDM6C protein gel.

Recombinant KDM6C protein gel.
KDM6C protein was run on an 8% SDS-PAGE gel and stained with Coomassie Blue.

for Recombinant KDM6C proteinStorage

Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Recombinant KDM6C proteinGuarantee

This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.

 

Technical Data Sheet

Recombinant KDM6C protein
 

Data Thumbnails

Recombinant KDM6C protein gel.

Recombinant KDM6C protein gel.
(Click to enlarge and view details)