Hbo1 antibody (pAb)

for Hbo1 antibody (pAb)Background

Hbo1 (HAT binding to ORC1) is a MYST-family histone acetyltransferase (HAT) that forms a complex with ING4/5, JADE1/2/3, and Eaf6, which is found enriched on coding regions of genes, supporting a role in transcriptional elongation. In addition, Hbo1 is thought to participate in events controlling the initiation of DNA replication.

for Hbo1 antibody (pAb)Immunogen

This antibody was raised against a synthetic peptide containing amino acids 158-172 of human Hbo1.

for Hbo1 antibody (pAb)Application Notes

This Hbo1 antibody has been validated for use in Western blotting (1:500 - 1:2,000 dilution). Hbo1 is chromatin-associated and can be detected by Western blot in whole-cell extracts or in the chromatin fraction of a nuclear extract. Overnight incubation with this antibody recommended for Western blotting.

for Hbo1 antibody (pAb)Buffer

Rabbit serum containing 30% glycerol and 0.035% sodium azide.

for Hbo1 antibody (pAb)Positive Control

Active Motif's HeLa whole-cell extract (Catalog No. 40050) can be used as a positive control for Hbo1 antibody.

for Hbo1 antibody (pAb)References

This antibody was used in Iizuka et al (2006) Mol. Cell Biol. 26:1098.

for Hbo1 antibody (pAb)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for Hbo1 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.