CENP-E antibody (mAb)

for CENP-E antibody (mAb) (Clone 1H12)Background

Centrosome-associated protein E (CENP-E) is a kinesin-like protein and an integral component of kinetochore fibers that link centromeres to spindle microtubules. CENP-E localizes to kinetochores throughout all phases of mitotic chromosome movement. After the onset of anaphase it is released, and by telophase becomes bound to interzonal microtubules of the mitotic spindle. It is likely that CENP-E serves as a chromosome motor during anaphase.

for CENP-E antibody (mAb) (Clone 1H12)Immunogen

Full-length human CENP-E protein.

for CENP-E antibody (mAb) (Clone 1H12)Application Notes

This CENP-E antibody (Clone 1H12) has been validated for use in immunofluorescence (1 µg/ml dilution).

*This CENP-E antibody (Clone 1H12) can be used in Western blot to detect CENP-E if the protein has been first enriched by immunoprecipitation.

for CENP-E antibody (mAb) (Clone 1H12)Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide.

for CENP-E antibody (mAb) (Clone 1H12)Positive Control

Active Motif's HeLa nuclear extract (Catalog No. 36010) can be used as a positive control for CENP-E antibody (Clone 1H12).

for CENP-E antibody (mAb) (Clone 1H12)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for CENP-E antibody (mAb) (Clone 1H12)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.