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CoREST antibody (pAb)
| Catalog No: 39955 | Format: 100 µl | $340 | Buy Now |
| Catalog No: 39956 | Format: 10 µl | $70 | Buy Now |
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Applications Table
| Western Blot | Chromatin IP |
|---|---|
| 1:500 - 1:1,000 | — |
for CoREST antibody (pAb)Background
CoREST (REST corepressor 1, RCOR1) is a corepressor protein recruited by the REST, a neuronal gene-specific transcriptional repressor, to help repress neuron specific gene expression in non-neuronal cell lineages. CoREST is an essential component of the BHC repressor complex that also contains HDAC1, HDAC2, HMG20B/BRAF35, LSD1 (a lysine-4 specific histone demethylase) and PHF21A/BHC80. The Herpes Simplex virus ICP0 protein blocks the repression of viral genes by disrupting the interaction between CoREST and HDAC1/2.
for CoREST antibody (pAb)Immunogen
This CoREST antibody was raised against a synthetic peptide derived from the C-terminal region of human CoREST.
for CoREST antibody (pAb)Application Notes
This CoREST antibody has been validated for use in Western blotting (1:500 - 1:1,000).
for CoREST antibody (pAb)Buffer
Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 32 mM glycine, 0.07 mM EDTA, 30% glycerol, and 0.035% sodium azide.
for CoREST antibody (pAb)Positive Control
Active Motif's P19 nuclear extract (Catalog No. 36074) can be used as a positive control for Runx1 antibody.
CoREST antibody (pAb) tested by Western blot.
Nuclear extract of HEK293 cells (25 µg) probed with CoREST antibody (1:500 dilution).
for CoREST antibody (pAb)Storage
Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
for CoREST antibody (pAb)Guarantee
This product is for research use only and is not for use in diagnostic procedures. This product is guaranteed for 6 months from date of arrival.
Application Key
- ChIP = Chromatin Immunoprecipitation;
- DB = Dot Blot;
- ELISA = Enzyme-linked Immunosorbent Assay;
- EMSA = Electrophoretic Mobility Shift Assay
- FACS = Flow Cytometry;
- ICC = Immunocytochemistry;
- IF = Immunofluorescence;
- IHC = Immunohistochemistry;
- IP = Immunoprecipitation;
- MeDIP = Methyl-DNA Immunoprecipitation;
- WB = Western Blotting
