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RAR-γ antibody (mAb)

Clone: 4γ-7A11
Aliases: Retinoic Acid Receptor gamma, RARG, RARC, NR1B3
商品コード: 39973 Format: 100 µg ¥67,000 Buy Now
商品コード: 39974 Format: 10 µg ¥19,000 Buy Now

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Antibody Type:Monoclonal
Isotype:IgG1k
Purification:Protein G Chromatography
Host:Mouse
Molecular Weight:52 kDa
Reactivity:Human

Applications

Western Blot Validated Immunohistochemistry Validated Electrophoretic Mobility Shift Assay Validated

for RAR-g antibody (mAb) (Clone 4γ-7A11)Application Notes


Published Applications:
IHC
EMSA
WB
See references for more information. Individual optimization may be required.

for RAR-g antibody (mAb) (Clone 4γ-7A11)Immunogen

This RAR-γ antibody was raised against a recombinant protein corresponding to amino acids 428-441 (F-region) of human RARγ.

for RAR-g antibody (mAb) (Clone 4γ-7A11)Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

for RAR-g antibody (mAb) (Clone 4γ-7A11)References

for RAR-g antibody (mAb) (Clone 4γ-7A11)Background

Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-α, RAR-β and RAR-γ. RAR-γ has two splice isoforms. RAR-γ heterodimerizes with RXR and in the absence of ligand, the RAR/RXR dimer binds to hormone response elements complexed with co-repressor protein. Binding of agonist ligands to RAR results in dissociation of co-repressor and recruitment of coactivator protein which in turn promotes transcription of the downstream target gene into mRNA and eventually protein.

for RAR-g antibody (mAb) (Clone 4γ-7A11)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for RAR-g antibody (mAb) (Clone 4γ-7A11)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

RAR-γ antibody (mAb)