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p63 antibody (mAb)

Clone: 87C553
Aliases: TP63, AIS, KET, LMS, NBP, RHS, p40, p51, EEC3, OFC8, p73H, p73L, SHFM4, TP53L, TP73L, p53CP, TP53CP, B(p51A), B(p51B)
商品コード: 40974 Format: 100 µg ¥67,000 Buy Now

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Antibody Type:Monoclonal
Isotype:IgG1
Purification:Affinity Purified
Host:Mouse
Molecular Weight:63 kDa
Reactivity:Human

Applications

Western Blot Validated

for p63 antibody (mAb) (Clone 87C553)Application Notes


Validated Applications:
WB: 3 - 5 µg/ml dilution

For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all Blotto solutions may also reduce background. Individual optimization may be required.

for p63 antibody (mAb) (Clone 87C553)Immunogen

This p63 antibody was raised against a synthetic peptide corresponding to human p63.

for p63 antibody (mAb) (Clone 87C553)Buffer

PBS containing 0.02% sodium azide. Sodium azide is highly toxic.

for p63 antibody (mAb) (Clone 87C553)References

for p63 antibody (mAb) (Clone 87C553)Background

p63, also known as TP63 (for tumor protein p63), is a p53-related tumor protein with some structural resemblance to p53, and is therefore considered a tumor-suppressor protein. p63 has numerous isoforms arising from alternative splicing, resulting in 6 different C-termini. Overexpression of p63 promotes growth arrest and/or apoptosis in a manner similar to that seen with p53. It is associated with ectrodactyly-ectodermal dysplasia-cleft syndrome and Hay-Wells syndrome.

for p63 antibody (mAb) (Clone 87C553)Positive Control

Whole-cell extracts from 293 cells can be used as a positive control for p63 antibody.

for p63 antibody (mAb) (Clone 87C553)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for p63 antibody (mAb) (Clone 87C553)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

p63 antibody (mAb)