Active Motif,
Tools to analyze nuclear function,
Your CartYour Cart 0 items
Antibodies

STAT5B antibody (pAb)

Catalog No: 61137 Format: 100 µg $340 Buy Now
Catalog No: 61138 Format: 10 µg $70 Buy Now
Antibody Type:Polyclonal
Host:Rabbit
Isotype:IgG
Purification:Affinity Purified
Applications:WB
Reactivity:Human
Molecular Weight:90 kDa

Applications Table

Western Blot Chromatin IP
0.5 - 2 µg/ml

for STAT5B antibody (pAb)Background

STAT5A and STAT5B are encoded by separate genes but are 90% identical. They mediate gene expression in response to IL-2, IL-3, IL-7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. The STAT5A/B signaling pathway is involved in the transition of organ-confined prostate cancer to hormone-refractory disease. This implies that the active JAK2-STAT5A/B signaling pathway potentially provides the means for pharmacological intervention of clinical prostate cancer progression.

for STAT5B antibody (pAb)Immunogen

This STAT5B antibody was raised against a peptide in the C-terminal region of human STAT5B.

for STAT5B antibody (pAb)Application Notes

This STAT5B antibody has been validated for use in Western blotting (0.5 - 2 µg/ml dilution).

for STAT5B antibody (pAb)Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide.

 
STAT5B antibody (pAb) tested by Western blot.

STAT5B antibody (pAb) tested by Western blot.
STAT5B antibody detection by Western blot. The analysis was performed using K-562 cytosolic-cell extract (25 µg) and STAT5B antibody (pAb) at a 1 µg/ml dilution.

for STAT5B antibody (pAb)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for STAT5B antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of arrival.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FACS = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • WB = Western Blotting
 

Technical Data Sheet

STAT5B antibody (pAb)
 

Data Thumbnails

STAT5B antibody (pAb) tested by Western blot.

Western blot of STAT5B pAb.
(Click image to enlarge and see details).