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N-Myc antibody (pAb)
| Catalog No: 61185 | Format: 100 µl | $340 | Buy Now |
| Catalog No: 61186 | Format: 10 µl | $70 | Buy Now |
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Applications Table
| Western Blot | Chromatin IP |
|---|---|
| 1:500 - 1:2,000 | — |
for N-Myc antibody (pAb)Background
N-Myc (MYCN) is a member of the Myc family of proto-oncogenes. Myc family members play crucial roles in regulating cell proliferation, size and differentiation. N-Myc is required for proper development of the nervous system. Myc family proteins can induce malignant transformation inappropriately modulating gene transcription, leading to unchecked cell proliferation. Misexpression of N-Myc is often associated with pediatric neural cancers such as neuroblastoma, medulloblastoma and retinoblastoma.
for N-Myc antibody (pAb)Immunogen
This N-Myc antibody was raised against a peptide derived from the C-terminal region of human N-Myc.
for N-Myc antibody (pAb)Application Notes
This N-Myc antibody has been validated for use in Western blot (1:500 - 1:2,000). For optimal results, primary antibody incubations should be performed at 4°C. Individual optimization may be required.
for N-Myc antibody (pAb)Buffer
Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 32 mM glycine, 0.07 mM EDTA, 30% glycerol, and 0.035% sodium azide.
N-Myc antibody (pAb) tested by Western blot.
Nuclear extract (20 µg) of Kelly cells probed with N-Myc antibody at a dilution of 1:1,000.
for N-Myc antibody (pAb)Storage
Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
for N-Myc antibody (pAb)Guarantee
This product is guaranteed for 6 months from date of arrival.
Application Key
- ChIP = Chromatin Immunoprecipitation;
- DB = Dot Blot;
- ELISA = Enzyme-linked Immunosorbent Assay;
- EMSA = Electrophoretic Mobility Shift Assay
- FACS = Flow Cytometry;
- ICC = Immunocytochemistry;
- IF = Immunofluorescence;
- IHC = Immunohistochemistry;
- IP = Immunoprecipitation;
- MeDIP = Methyl-DNA Immunoprecipitation;
- WB = Western Blotting
