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CBX8 antibody (pAb)

Aliases: PC3, RC1
商品コード: 61237 Format: 100 µl ¥67,000 Buy Now
商品コード: 61238 Format: 10 µl ¥19,000 Buy Now

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Antibody Type:Polyclonal
Isotype:IgG
Purification:Affinity Purified
Host:Rabbit
Molecular Weight:45kD
Reactivity:Human

Applications

Western Blot Validated

for CBX8 antibody (pAb)Application Notes


Validated Applications:
WB: 1:500 dilution

for CBX8 antibody (pAb)Immunogen

This CBX8 antibody was raised against a peptide corresponding to the C-terminal region of human CBX8 (Chromobox protein homolog 8).

for CBX8 antibody (pAb)Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

for CBX8 antibody (pAb)References

 
CBX8 antibody (pAb) tested by Western blot.

CBX8 antibody (pAb) tested by Western blot.
Whole-cell extract of HeLa cells (20 µg) probed with CBX8 antibody (1:500).

for CBX8 antibody (pAb)Background

CBX8 (chromobox homolog 8, PC3, RC1) is a Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

for CBX8 antibody (pAb)Positive Control

Active Motif's HeLa whole-cell extract (Catalog No. 40050) can be used as a positive control for CBX8 antibody.

for CBX8 antibody (pAb)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for CBX8 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

CBX8 antibody (pAb)
 

Data Thumbnails

CBX8 antibody (pAb) tested by Western blot.

Western blot of CBX8 pAb.
(Click image to enlarge and see details.)