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FOXL2 antibody (pAb)

Aliases: BPES, PFRK, POF3, BPES1, PINTO
商品コード: 61283 Format: 100 µl ¥67,000 Buy Now
商品コード: 61284 Format: 10 µl ¥19,000 Buy Now

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Antibody Type:Polyclonal
Isotype:IgG
Purification:Affinity Purified
Host:Rabbit
Molecular Weight:40 kDa
Reactivity:Human

Applications

Western Blot Validated

for FOXL2 antibody (pAb)Application Notes


Validated Applications:
WB: 1:500 - 1:1,000 dilution

for FOXL2 antibody (pAb)Immunogen

This FOXL2 antibody was raised against a peptide within the N-terminal region of human FOXL2.

for FOXL2 antibody (pAb)Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

for FOXL2 antibody (pAb)References

 
FOXL2 antibody (pAb) tested by Western blot.

FOXL2 pAb tested by Western blot.
Detection of FOXL2 by Western blot analysis. Nuclear extract of OVCAR-3 cells (30 µg) was probed with FOXL2 pAb at a 1:500 dilution.

for FOXL2 antibody (pAb)Background

FOXL2 (forkhead box L2, BPES, PFRK, POF3, BPES1, PINTO) is a transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

for FOXL2 antibody (pAb)Positive Control

Active Motif's NIH:OVCAR-3 nuclear extract (Catalog No. 36081) can be used as a positive control for FOXL2 antibody.

for FOXL2 antibody (pAb)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for FOXL2 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

FOXL2 antibody (pAb)
 

Data Thumbnails

FOXL2 antibody (pAb) tested by Western blot.

Western blot of FOXL2 pAb.
(Click image to enlarge and see details.)