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KAT6a antibody (mAb)

Clone: 2MOZ-2D4
Aliases: MOZ, Myst3, Zfp220, 1500036M03, 9930021N24Rik
商品コード: 61327 Format: 100 µg ¥67,000 Buy Now

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Antibody Type:Monoclonal
Isotype:IgG1k
Purification:Protein A Chromatography
Host:Mouse
Molecular Weight:290 kDa
Reactivity:Human, Mouse

Applications

ChIP Validated Western Blot Validated Immunoprecipitation Validated

for Kat6a antibody (mAb) (Clone 2MOZ-2D4)Application Notes


Published Applications:
ChIP
IP
WB
See references for more information. Individual optimization may be required.

for Kat6a antibody (mAb) (Clone 2MOZ-2D4)Immunogen

This antibody was raised against a peptide corresponding to amino acid residue(s) 856-869 of mouse Kat6a.

for Kat6a antibody (mAb) (Clone 2MOZ-2D4)Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 32 mM glycine, 0.07 mM EDTA, 30% glycerol, and 0.035% sodium azide.

for Kat6a antibody (mAb) (Clone 2MOZ-2D4)References

for Kat6a antibody (mAb) (Clone 2MOZ-2D4)Background

Kat6a (K(lysine) acetyltransferase 6a, MOZ, MYST3) is a histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2.

Chromatin IP Assays

This antibody has been validated for use in ChIP and/or ChIP-Seq, and can be used with Active Motif's ChIP-IT® High Sensitivity Kit or our magnetic bead-based ChIP-IT® Express Kits. For an overview of all of our ChIP products, please visit our Chromatin IP Page to learn about ChIP products designed for use with KAT6a antibody (mAb).

Bridging Antibody to Improve ChIP, MeDIP and IP

Some isotypes of mouse IgG antibodies do not bind well to protein G-conjugated agarose/magnetic beads, which are commonly used in ChIP, MeDIP and IP experiments. Capture efficiency can be improved by including an anti-mouse IgG bridging antibody because it binds with a strong affinity to both the protein G beads and the mouse IgG antibody. By increasing the affinity of the mouse primary antibody for the protein G bead, the Bridging Antibody for Mouse IgG can help improve the results of all ChIP, MeDIP and IP experiments that use KAT6a antibody (mAb).

for Kat6a antibody (mAb) (Clone 2MOZ-2D4)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for Kat6a antibody (mAb) (Clone 2MOZ-2D4)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

KAT6a antibody (mAb)