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CABIN1 antibody (pAb)

Aliases: CAIN, PPP3IN
商品コード: 61597 Format: 100 µl ¥67,000 Buy Now
商品コード: 61598 Format: 10 µl ¥19,000 Buy Now

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Antibody Type:Polyclonal
Isotype:IgG
Purification:Affinity Purified
Host:Rabbit
Molecular Weight:280 kDa
Reactivity:Human

Applications

Western Blot Validated Immunoprecipitation Validated

for CABIN1 antibody (pAb)Application Notes


Validated Applications:
IP: 10 µl per IP
WB: 1:500 dilution

Individual optimization may be required.

for CABIN1 antibody (pAb)Immunogen

This antibody was raised against a peptide within the C-terminal region of human CABIN1.

for CABIN1 antibody (pAb)Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

for CABIN1 antibody (pAb)References

 
CABIN1 antibody (pAb) tested by Western blot.

CABIN1 antibody (pAb) tested by Immunoprecipitation / Western blot.
10 µg of HIRA antibody (mAb), catalog no 39555, (lane 1) or 10 µl of CABIN1 antibody (pAb) (lane 2) was used to immunoprecipitate CABIN1 from 1mg of U2OS nuclear extract. 10 µg of rabbit IgG was also used as a negative control (lane 3). The immunoprecipitated protein was detected by Western blotting using CABIN1 antibody at a dilution of 1:500.

for CABIN1 antibody (pAb)Background

CABIN1 (calcineurin-binding protein 1) may be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Component of a complex that includes at least ASF1A, CABIN1, HIRA, Histone H3.3 and UBN1.

for CABIN1 antibody (pAb)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for CABIN1 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

CABIN1 antibody (pAb)
 

Data Thumbnails

CABIN1 antibody (pAb) tested by Western blot.

Western blot of CABIN1 pAb.
(Click image to enlarge and see details.)