Histone PTM Multiplex Service
profile histone modifications in multiplex
Technology covered under U.S. Patent No. 8367334 b2.
Histone PTM Services Quote Request
- Minimal cell requirement of 250,000 cells is sufficient to quantify 13 histone modifications.
- Detects ≥ 10% difference between samples.
- Controls include total H3 and samples containing known PTM changes.
Histone PTM Quantitation Service includes:
- Assay design.
- Sample preparation.
- Completion of the Luminex assay.
- Data analysis.
|Histone PTM Quantitation, 8 Sample Service||25062||Get Quote|
|Luminex Histone PTM Bead Set||25063||Get Quote|
Figure 1: Data from our Histone PTM Quantitation Service shows increased histone acetylation in response to SAHA-mediated HDAC inhibition
Figure 2: HDAC inhibitor (VPA) treatment increases histone acetylation with concomitant reductions in H3K27me2
Figure 3: EZH2 inhibition results in decreased H2K27me3 levels