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RXR-α antibody (mAb)
| RRID: AB_2793479 |
| Clone: 4RX-3A2 |
| Aliases: Rxra, Nr2b1, RXRalpha1 |
| Catalog No: 61029 | Format: 100 µg | Discontinued | |
Applications
Application Notes
This product has been discontinued
Published Applications:
IP
EMSA
WB
See references for more information. Individual optimization may be required.
Immunogen
This RXR-alpha antibody was raised against a recombinant protein corresponding to the C-terminal region of mouse RXR-alpha.
Buffer
Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.
Background
RXR-α (Retinoid X Receptor alpha, NR2B1) is a nuclear receptor that mediates the biological effects of retinoids by its involvement in retinoic acid-mediated gene activation. RXR-α exerts its action by binding, as a homodimer or a heterodimer, to specific sequences in the promoters of target genes and regulating their transcription. RXR-α is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.
Positive Control
Active Motif's MCF-7 nuclear extract (Catalog No. 36017) can be used as a positive control for RXR-α antibody.
Storage
Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.
Guarantee
This product is guaranteed for 6 months from date of receipt.
This product is for research use only and is not for use in diagnostic procedures.
Application Key
- ChIP = Chromatin Immunoprecipitation;
- ChIP = ChIP Sequencing;
- CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
- CUT&Tag = Cleavage Under Targets and Tagmentation;
- DB = Dot Blot;
- ELISA = Enzyme-linked Immunosorbent Assay;
- EMSA = Electrophoretic Mobility Shift Assay
- FC = Flow Cytometry;
- ICC = Immunocytochemistry;
- IF = Immunofluorescence;
- IHC = Immunohistochemistry;
- IP = Immunoprecipitation;
- MeDIP = Methyl-DNA Immunoprecipitation;
- NEU = Neutralizing;
- WB = Western Blotting
