YOUR CART
At Active Motif, we develop innovative cell biology-based research tools and biocomputing resources that help researchers elucidate the function, regulation and interactions of the genes and their encoded proteins. Our goal is to provide our customers with high-quality products complemented by superior service & support.
NEW AND NOTABLE PRODUCTS
- New 5-Hydroxymethylcytidine Antibody for MeDIP
Active Motif now offers the first commercially available antibody against 5-Hydroxymethylcytosine for MeDIP and IF. This novel form of DNA methylation represents a potential mechanism by which 5-methylcytosine is removed. - Methylated DNA Standard Kit for the Study of DNA Methylation
Try our new Methylated DNA Standard Kit for experiments examining the different types of DNA methylation. It includes DNA derived from the APC promoter that has no methylation, 5-methylcytosine methylation or 5-hydroxymethylcytosine methylation. Also included are specific primers to aid in detection by PCR. - Easy ELISAs for Histone Modification Detection
Screen samples for changes in histone methylation or phosphorylation using Active Motif's Histone Modification ELISAs. Kits are available to detect Histone H3 phospho Ser10, Histone H3 phospho Ser28, Histone H3 Lys4 (H3K4), Histone H3 Lys9 (H3K9) and Histone H3 Lys27 (H3K27), as well as Total Histone H3. - Screen Extracts or Proteins for Deubiquitination Activity
DUB-Detector™ provides a simple fluorescent assay that can be used to detect the activity of deubiquitination enzymes (DUBs) in either kinetic or endpoint analysis. The spectral characteristics (Ex. 485 nm, Em. 535 nm) used for detection eliminate autofluorescence and are also well suited for small molecule screening. - Representative Amplification of Genomic DNA
GenoMatrix™ provides up to 500-fold amplification from as little as 10 ng of genomic DNA, while maintaining sequence representation of the sample.
- MODified™ Histone Peptide Array and FREE Software
Screen 384 different histone modification combinations in a single experiment. The MODified™ Histone Peptide Array allows you to screen antibodies or enzymes for interactions with histones and their post-translational modifications on the N-terminal tails of H2A, H2B, H3 and H4. - Histone Antibody Supplies You Can Count On
We design and manufacture our own antibodies, rather than just reselling them. So, we won't run out of abs that are important to your work, like Histone H3 trimethyl Lys4 or our other over 100 antibodies directed against histones and specific histone modifications. Count on it! - DNMT Activity / Inhibition Assay
This fast, non-radioactive assay utilizes the unique binding properties of methyl CpG binding domain (MBD) proteins towards methylated DNA to detect nanogram levels of DNMT1, DNMT3a & DNMT3b activity. - Non-radioactive EMSA
Active Motif now offers a chemiluminescent EMSA kit to detect protein-DNA binding. The Gelshift™ Chemiluminescent EMSA Kit allows you to study variant transcription factor binding sites using proven buffers and reagents. - Expand the Utility of ChIP
magnetic beads make ChIP faster & more effective, which has enabled new kits for performing high-throughput ChIP, as well as sequential ChIP.
