At Active Motif, we develop innovative cell biology-based research tools and biocomputing resources that help researchers elucidate the function, regulation and interactions of the genes and their encoded proteins. Our goal is to provide our customers with high-quality products complemented by superior service & support.
NEW PRODUCTS
- Mitotic Marker ELISAs
New sandwich ELISA assays are now available to screen for mitotic markers Histone H3 phospho Ser10 and Histone H3 phospho Ser28. These sensitive assays make it easy to screen for changes in the levels of histone H3 phosphorylation. - Histone Modification ELISAs
Active Motif has used its expertise in making antibodies specific to histone modifications to develop sandwich ELISAs that quantitate the methylation levels of Histone H3 Lys9 (H3K9) and Histone H3 Lys27 (H3K27), as well as Total Histone H3. - Methylation Analysis of
CpG DNA Regions
MethylCollector™ Ultra can isolate CpG-methylated DNA from just 200 cells, while UnMethylCollector™ isolates DNA fragments with only a single unmethylated CpG, enabling the study of hypomethylated CpG islands. - Representative Amplification of Genomic DNA
GenoMatrix™ provides up to 500-fold amplification from as little as 10 ng of genomic DNA, while maintaining sequence representation of the sample.
NEW PRODUCTS (cont.)
- DNMT Activity / Inhibition Assay
This fast, non-radioactive assay utilizes the unique binding properties of methyl CpG binding domain (MBD) proteins towards methylated DNA to detect nanogram levels of DNMT1, DNMT3a & DNMT3b activity. - Non-radioactive EMSA
Active Motif now offers a chemiluminescent EMSA kit to detect protein-DNA binding. The Gelshift™ Chemiluminescent EMSA Kit allows you to study variant transcription factor binding sites using proven buffers and reagents. - Identify Proteins that Bind Methylated H3K9 and H3K27
HiLite™ Binding Assays use Fluorescence Polarization to measure binding of chromatin-modifying proteins to methylated histone tails. - New Histone Antibodies
high-quality antibodies directed against histones and specific histone modifications, such as our collection of antibodies directed against Histone H3 lysine 4 methylation, which is a marker for active genes. - Expand the Utility of ChIP
magnetic beads make ChIP faster & more effective, which has enabled new kits for performing high-throughput ChIP, as well as sequential ChIP.



