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Ultraconserved Enhancers and Enhancer Redundancy (Diane Dickel)
Episode 50
June 10, 2021
In our 50th episode of the Epigenetics Podcast, we caught up with Dr. Diane Dickel from Lawrence Berkeley National Laboratory to talk about her work on ultraconserved enhancers and enhancer redundancy. We discuss how Diane Dickel and her team try to identify and characterize enhancers at a genomic scale and use CRISPR/CAS9 to mutate enhancer sequences in order to understand sequence dependent functional relevance. In addition, we chat about what ultraconservation actually means, how enhancer redundancy works and how Diane Dickel dealt with a failed PhD project.
