Active Motif,
Tools to analyze nuclear function,
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Histone Acetylation (HAT & HDAC)

epigenetic modulators of HATs & HDACs

Histone acetylation is a reversible reaction that occurs on the lysine residues of histone tails. Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl coenzyme A, while histone deacetylases (HDACs) perform the antagonistic action of removing the acetyl group. Histone acetylation plays an important role in the modulation of chromatin condensation and transcriptional regulation.

Active Motif offers several small molecules to study the effect of changes in HAT and HDAC activity.

 
Name Appl. Format Cat No. 価格 (税抜)  
Apicidin HDAC Inhibitor 5 mg 14040 ¥50,000 Buy Now
1 mg 14041 ¥18,000 Buy Now
BML-210 HDAC Inhibitor 25 mg 14048 ¥73,000 Buy Now
5 mg 14049 ¥23,000 Buy Now
C646 p300/CBP Inhibitor 25 mg 14052 ¥78,000 Buy Now
5 mg 14053 ¥26,000 Buy Now
CI-994 HDAC Inhibitor 25 mg 14092 ¥53,600 Buy Now
5 mg 14093 ¥15,000 Buy Now
CPTH2 Gcn5P Inhibitor 25 mg 14094 ¥53,600 Buy Now
5 mg 14095 ¥15,000 Buy Now
CTPB p300 Activator 25 mg 14064 ¥78,000 Buy Now
5 mg 14065 ¥30,000 Buy Now
CUDC-101 HDAC and Receptor Tyrosine Kinase Inhibitor 25 mg 14060 ¥104,000 Buy Now
5 mg 14061 ¥34,000 Buy Now
Embelin PCAF Inhibitor 50 mg 14118 ¥46,000 Buy Now
10 mg 14119 ¥10,300 Buy Now
Garcinol p300/pCAF Inhbitor 50 mg 14076 ¥64,000 Buy Now
10 mg 14077 ¥20,000 Buy Now
HPA (Hexyl-4-pentynoic acid) HDAC Inhibitor 50 mg 14034 ¥41,000 Buy Now
10 mg 14035 ¥10,000 Buy Now
Mocetinostat HDAC Inhibitor 25 mg 14136 ¥57,000 Buy Now
5 mg 14137 ¥18,000 Buy Now
MS-275 HDAC Inhibitor 25 mg 14042 ¥50,000 Buy Now
5 mg 14043 ¥19,000 Buy Now
Panobinostat Class I and II HDAC Inhibitor 25 mg 14044 ¥50,000 Buy Now
5 mg 14045 ¥19,000 Buy Now
Phenylbutyrate Na HDAC Inhibitor 1 g 14033 ¥15,000 Buy Now
Romidepsin HDAC Inhibitor 1 mg 14083 ¥46,000 Buy Now
TM-2-51 HDAC8 Activator 50 mg 14096 ¥37,600 Buy Now
10 mg 14097 ¥10,300 Buy Now
Trichostatin A HDAC Inhibitor 5 mg 14038 ¥85,000 Buy Now
1 mg 14039 ¥33,000 Buy Now
Tubastatin A hydrochloride HDAC6 Inhibitor 25 mg 14084 ¥73,000 Buy Now
5 mg 14085 ¥25,000 Buy Now
Valproic Acid, sodium salt HDAC Inhibitor 5 g 14021 ¥8,000 Buy Now
Vorinostat (SAHA) HDAC Inhibitor 50 mg 14026 ¥64,000 Buy Now
10 mg 14027 ¥20,000 Buy Now
Piceatannol SIRT1 Activator 25 mg 14036 ¥43,000 Buy Now
5 mg 14037 ¥14,000 Buy Now