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BML-278

Aliases: N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine
商品コード: 14024 Format: 25 mg ¥54,000 Buy Now
商品コード: 14025 Format: 5 mg ¥18,000 Buy Now
Application: Sirtuins

for BML-278Chemical Properties

MW = 391.5
C24H25NO4
CAS Not found
MP = 141-143°C
>98% (TLC); NMR (Conforms)

for BML-278Description

A structurally novel activator of SIRT1 (EC150= 1 M). Displays selectivity over SIRT2 and SIRT3 (EC150= 25 M and 50 M respectively). Cell permeable.

for BML-278Contents

Off white powder. May be dissolved in DMSO (5 mg/ml.

for BML-278Storage Conditions

Store desiccated as supplied at room temperature for up to 2 years. Store solutions at -20°C for up to 3 months.

for BML-278References

1. A Mai et al. J. Med. Chem. 2009, 52:5496

 
Chemical structure of BML-278.

Chemical structure of BML-278.

 

Technical Data Sheet

BML-278
 

Data Thumbnails

Chemical structure of BML-278.

Chemical structure of BML-278.
(Click image to enlarge.)