Active Motif,
Tools to analyze nuclear function,
Your CartYour Cart 0 items

Garcinol

商品コード: 14076 Format: 50 mg ¥64,000 Buy Now
商品コード: 14077 Format: 10 mg ¥20,000 Buy Now
Application: Histone Acetylation (HAT & HDAC)

for GarcinolChemical Properties

MW = 602.8
C38H50O6
CAS 78824-30-3
>97% (TLC); NMR (Conforms)

for GarcinolDescription

Potent inhibitor of histone acetyltransferases p300 (IC50 = 7 M) and pCAF (IC50 = 5 M)(ref 1). Induces apoptosis in various cell lines (ref 2). Promotes expansion of human hematopoietic stem cells (ref 3). Cell permeable.

for GarcinolContents

Yellow solid. May be dissolved in DMSO (25 mg/ml); Ethanol (25 mg/ml).

for GarcinolStorage Conditions

Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 2 months.

for GarcinolReferences

1. K Balasubramanyam et al. J. Biol. Chem. 2004, 279:33716
2. MA Parasramka et al. Nutr. Cancer 2011, 63:456
3. T Nishino et al. PLoS One 2011, 6:e24298

 
Chemical structure of Garcinol.

Chemical structure of Garcinol.

 

Technical Data Sheet

Garcinol
 

Data Thumbnails

Chemical structure of Garcinol.

Chemical structure of Garcinol.
(Click image to enlarge.)