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Antibodies

LAP2 alpha antibody (mAb)

Clone: 3A3
Catalog No: 39267 Format: 200 µl $340 Buy Now
Catalog No: 39268 Format: 10 µl $70 Buy Now
Antibody Type:Monoclonal
Host:Mouse
Isotype:IgG
Purification:Ascites
Applications:WB
Reactivity:Human
Molecular Weight:80 kDa

Applications Table

Western Blot Chromatin IP
1:1,000 - 1:2,000

for LAP2 alpha antibody (mAb) (Clone 3A3)Background

LAP2 α (Lamin Associated Polypeptide, alpha isoform, Thymopoietin) is a nucleoplasmic protein that oligomerizes and binds Hsp70 and Hsc70. It is involved in the organization of the nuclear structure through its interaction with A-type Lamins (Lamin B1). LAP2 α regulates the cell cycle through its interaction with the Rb protein.

for LAP2 alpha antibody (mAb) (Clone 3A3)Immunogen

This LAP2 alpha antibody was raised against a peptide including the C-terminus of human LAP2 alpha.

for LAP2 alpha antibody (mAb) (Clone 3A3)Application Notes

This LAP2 alpha antibody has been validated for use in Western blotting (1:1,000 - 1:2,000 dilution).

for LAP2 alpha antibody (mAb) (Clone 3A3)Buffer

Ascites containing 30% glycerol and 0.035% sodium azide.

for LAP2 alpha antibody (mAb) (Clone 3A3)Positive Control

Active Motif's HeLa nuclear extract (Catalog No. 36010) can be used as a positive control for LAP2 alpha antibody (Clone 3A3).

for LAP2 alpha antibody (mAb) (Clone 3A3)References

This antibody was used in Dorner et al (2006) J Cell Biol 173:83.

 
LAP2 alpha mAb (Clone 3A3) tested by Western blot.

LAP2 alpha mAb (Clone 3A3) tested by Western blot.
Detection of LAP2 alpha by Western blot. The analysis was performed using HeLa nuclear extract and LAP2 alpha mAb (Clone 3A3) at a 1:2,000 dilution.

for LAP2 alpha antibody (mAb) (Clone 3A3)Storage

Antibodies in solution can be stored at -20°C for 2 years. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

for LAP2 alpha antibody (mAb) (Clone 3A3)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FACS = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • WB = Western Blotting
 

Technical Data Sheet

LAP2 alpha antibody (mAb)
 

Data Thumbnails

LAP2 alpha mAb (Clone 3A3) tested by Western blot.

Western blot of LAP2 alpha mAb.
(Click image to enlarge and see details.)