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IRF-4 antibody (pAb)

Aliases: MUM1, LSIRF, NF-EM5
商品コード: 61511 Format: 100 µl ¥67,000 Buy Now
商品コード: 61512 Format: 10 µl ¥19,000 Buy Now

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Antibody Type:Polyclonal
Isotype:IgG
Purification:Affinity Purified
Host:Rabbit
Molecular Weight:52 kDa
Reactivity:Human

Applications

Western Blot Validated

for IRF-4 antibody (pAb)Application Notes


Validated Applications:
WB: 1:500 - 1:2,000 dilution

for IRF-4 antibody (pAb)Immunogen

This antibody was raised against a peptide within the C-terminal region of human IRF-4.

for IRF-4 antibody (pAb)Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

for IRF-4 antibody (pAb)References

 
IRF-4 antibody (pAb) tested by Western blot.

IRF-4 (pAb) tested by Western blot.
IRF-4 detection by Western blot. The analysis was performed using Ramos whole-cell extract (10 µg) and IRF-4 antibody (pAb) at a 1:500 dilution.

for IRF-4 antibody (pAb)Background

IRF-4 (Interferon Regulatory Factor 4) is a transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).

for IRF-4 antibody (pAb)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for IRF-4 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

IRF-4 antibody (pAb)
 

Data Thumbnails

IRF-4 antibody (pAb) tested by Western blot.

Western blot of IRF-4 pAb.
(Click image to enlarge and see details.)