Active Motif,
Tools to analyze nuclear function,
Your CartYour Cart 0 items
抗体

RAR-α antibody (mAb)

Clone: 9α-9A6
Aliases: Retinoic Acid Receptor Alpha, RARA, RAR, NR1B1
商品コード: 39971 Format: 100 µg ¥67,000 Buy Now

Request a quote for a bulk orderBulk Order Button


Antibody Type:Monoclonal
Isotype:IgG1k
Purification:Protein G Chromatography
Host:Mouse
Molecular Weight:52 kDa
Reactivity:Human, Mouse

Applications

Western Blot Validated Immunohistochemistry Validated Electrophoretic Mobility Shift Assay Validated

for RAR-a antibody (mAb) (Clone 9α-9A6)Application Notes


Published Applications:
EMSA
IHC
WB
See references for more information. Individual optimization may be required.

for RAR-a antibody (mAb) (Clone 9α-9A6)Immunogen

This RAR-a antibody was raised against a recombinant protein corresponding to amino acids 420-443 (the F region) of human RARa.

for RAR-a antibody (mAb) (Clone 9α-9A6)Buffer

Purified IgG in 70 mM Tris (pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

for RAR-a antibody (mAb) (Clone 9α-9A6)References

for RAR-a antibody (mAb) (Clone 9α-9A6)Background

Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-α, RAR-β and RAR-γ. RAR-α (Nuclear receptor subfamily 1 group B member 1, NR1B1) interacts with NCoA3, NCoA6, NCoA7 and MLL to activate transcription of target genes. Chromosomal aberrations of RAR-α are sometimes involved in Promyelocytic leukemia.

for RAR-a antibody (mAb) (Clone 9α-9A6)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for RAR-a antibody (mAb) (Clone 9α-9A6)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting
 

Technical Data Sheet

RAR-α antibody (mAb)