Sox11 antibody (pAb)

RRID: AB_2793541
Aliases: SRY-Box 11
Catalog No: 61181 Format: 100 µl ¥86,000 Buy
Catalog No: 61182 Format: 10 µl ¥24,000 Buy

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Antibody Type:
Polyclonal
Isotype:
IgG
Purification:
Affinity Purified
Host:
Rabbit
Molecular Weight:
65 kDa
Reactivity:
Human

Applications

Western Blot Validated

Application Notes

Applications Validated by Active Motif:
WB: 1:500 - 1:1,000 dilution

Immunogen

This Sox11 antibody was raised against a peptide from the N-terminus of human Sox11.

Buffer

Purified rabbit IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

 

Sox11 pAb tested by Western blot.
Nuclear extract of Y-79 cells (20 µg) was probed with Sox11 pAb (1:500 dilution).

Background

Sox11 (SRY-box containing protein 11) is a member of a family of transcription factors containing an HMG DNA-binding domain. Sox11 is important for the development of nervous system. Sox11 is upregulated in a variety of tumor types, including medulloblastomas, gliomas and epithelial ovarian tumors. In B cell lymphomas, information regarding the expression of Sox11 aids in diagnosis and prognosis. Sox11 also functions as a tumor suppressor in glioma-initiating cells.

Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Guarantee

This product is guaranteed for 12 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • ChIP = ChIP Sequencing;
  • CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
  • CUT&Tag = Cleavage Under Targets and Tagmentation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • NEU = Neutralizing;
  • WB = Western Blotting