Histone Acetylation (HAT & HDAC)

epigenetic modulators of HATs & HDACs

Histone acetylation is a reversible reaction that occurs on the lysine residues of histone tails. Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl coenzyme A, while histone deacetylases (HDACs) perform the antagonistic action of removing the acetyl group. Histone acetylation plays an important role in the modulation of chromatin condensation and transcriptional regulation.

Active Motif offers several small molecules to study the effect of changes in HAT and HDAC activity.

 
Name Appl. Format Cat No. Price  
Apicidin HDAC Inhibitor 5 mg 14040 ¥48,000 Buy
1 mg 14041 ¥17,200 Buy
BML-210 HDAC Inhibitor 25 mg 14048 ¥44,000 Buy
5 mg 14049 ¥14,900 Buy
C646 p300/CBP Inhibitor 25 mg 14052 ¥40,000 Buy
5 mg 14053 ¥13,800 Buy
CI-994 HDAC Inhibitor 25 mg 14092 ¥53,000 Buy
5 mg 14093 ¥19,500 Buy
CPTH2 Gcn5P Inhibitor 25 mg 14094 ¥53,000 Buy
5 mg 14095 ¥19,500 Buy
CTPB p300 Activator 25 mg 14064 ¥46,000 Buy
5 mg 14065 ¥12,600 Buy
CUDC-101 HDAC and Receptor Tyrosine Kinase Inhibitor 25 mg 14060 ¥92,000 Buy
5 mg 14061 ¥28,700 Buy
Embelin PCAF Inhibitor 50 mg 14118 ¥46,000 Buy
10 mg 14119 ¥12,600 Buy
Garcinol p300/pCAF Inhbitor 50 mg 14076 ¥61,000 Buy
10 mg 14077 ¥18,400 Buy
HPA (Hexyl-4-pentynoic acid) HDAC Inhibitor 50 mg 14034 ¥25,300 Buy
10 mg 14035 ¥10,300 Buy