Multiple Challenges in ChIP (Adam Blattler)
June 9, 2017
In this first episode of the Active Motif Epigenetics Podcast we chatted with Dr. Adam Blattler from the R&D team at Active Motif and discussed the multiple challenges of ChIP, the critical points of the ChIP protocol, as well as possible pitfalls.
Chromatin immunoprecipitation has become a very powerful method to study protein-DNA interactions, identify the binding profiles of DNA binding proteins, and determine whether specific proteins are associated with specific genomic regions. However, the workflow is complicated and involves many steps, so extensive experience and optimization are often required to achieve the best results.
Check out our Guide to Generating the Best ChIP Data on our blog for more details.