KDM4C antibody (pAb)

RRID: AB_2793735
Aliases: GASC1, JHDM3C, JMJD2C, TDRD14C
Catalog No: 61687 Format: 100 µl ¥86,000 Buy
Catalog No: 61688 Format: 10 µl ¥24,000 Buy

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Antibody Type:
Polyclonal
Isotype:
IgG
Purification:
Affinity Purified
Host:
Rabbit
Molecular Weight:
142 kDa
Reactivity:
Monkey

Applications

Western Blot Validated

Application Notes

Applications Validated by Active Motif:
WB: 1:500 dilution

For JMJD2C / KDM4C, we also offer AbFlex® JMJD2C / KDM4C Recombinant Antibody (rAb). For details, see Catalog No. 91307.

Immunogen

This antibody was raised against a peptide within human KDM4C.

Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

 

KDM4C antibody (pAb) tested by Western blot.
COS-7 nuclear extract (25 µg per lane) was probed with KDM4C pAb at a 1:500 dilution.
Lane 1: No treatment.
Lane 2: Cells treated with CoCl2.

Background

KDM4C (Lysine (K)-Specific Demethylase 4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Guarantee

This product is guaranteed for 12 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • ChIP = ChIP Sequencing;
  • CUT&RUN = Cleavage Under Targets and Release Using Nuclease;
  • CUT&Tag = Cleavage Under Targets and Tagmentation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • NEU = Neutralizing;
  • WB = Western Blotting