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TRIM37 antibody (pAb)

Aliases: MUL, POB1, TEF3
商品コード: 61747 Format: 100 µl ¥68,400 Buy Now
商品コード: 61748 Format: 10 µl ¥20,000 Buy Now

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Antibody Type:Polyclonal
Purification:Affinity Purified
Molecular Weight:120 kDa
Reactivity:Human, Mouse


Western Blot Validated

for TRIM37 antibody (pAb)Application Notes

Validated Applications:
WB: 1:500 - 1:2,000 dilution

for TRIM37 antibody (pAb)Immunogen

This antibody was raised against a peptide within the C-terminal region of human TRIM37.

for TRIM37 antibody (pAb)Buffer

Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic.

for TRIM37 antibody (pAb)References

TRIM37 antibody (pAb) tested by Western blot.

TRIM37 antibody (pAb) tested by Western blot.
TRIM37 antibody detection by Western blot. The analysis was performed using 30 µg of human MDA-MB-231 nuclear cell extract (Lane 1) or mouse F9 nuclear extract (Lane 2) and TRIM37 antibody at a 1:500 dilution.

for TRIM37 antibody (pAb)Background

TRIM37 (Tripartite Motif Containing 37) is an E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).

for TRIM37 antibody (pAb)Storage

Some products may be shipped at room temperature. This will not affect their stability or performance. Upon receipt, unconjugated antibodies may be stored at -20°C for up to 2 years. Fluorophore- & enzyme-conjugated antibodies should be stored at 4°C. Fluorophore-conjugated antibodies should be protected from light. Keep reagents on ice when not in storage; to avoid repeated freeze/thaw cycles, we recommend aliquoting items that will be stored frozen into single-use fractions prior to freezing.

for TRIM37 antibody (pAb)Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

Application Key

  • ChIP = Chromatin Immunoprecipitation;
  • DB = Dot Blot;
  • ELISA = Enzyme-linked Immunosorbent Assay;
  • EMSA = Electrophoretic Mobility Shift Assay
  • FC = Flow Cytometry;
  • ICC = Immunocytochemistry;
  • IF = Immunofluorescence;
  • IHC = Immunohistochemistry;
  • IP = Immunoprecipitation;
  • MeDIP = Methyl-DNA Immunoprecipitation;
  • TR-FRET = Time-Resolved Fluorescence Resonance Energy Transfer;
  • WB = Western Blotting

Technical Data Sheet

TRIM37 antibody (pAb)

Data Thumbnails

TRIM37 antibody (pAb) tested by Western blot.

Western blot of TRIM37 pAb.
(Click image to enlarge and see details.)