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DU 145 nuclear extract

商品コード: 36037 Format: 200 µg ¥31,400 Buy Now

for DU 145 nuclear extractContents

200 µg of DU 145 nuclear extract at 5.68 µg/µl.

for DU 145 nuclear extractBackground

DU 145 nuclear extract was prepared from cell cultures of the human prostate carcinoma DU 145 cell line. The DU 145 cell line was originally derived from a brain metastasis of a male patient with prostate carcinoma and lymphocytic leukemia. In culture, these cells form epithelial-like monolayers that contain microvilli, tonofilaments and desmosomes. The DU 145 cell line, along with the PC3 cell line, are considered to be the classic prostate cancer cell lines and are most commonly used as in vitro models for prostate cancer growth and behavior. Prostate cancer is the second most common neoplasia in men. These cells exhibit moderate metastatic potential and have been demonstrated to induce adenocarcinoma in nude mice. DU 145 cells are not hormone sensitive, but do express androgen and NFκB-activating receptors, and are weakly positive for acid phosphatase.

for DU 145 nuclear extractApplication Notes

DU 145 nuclear extract is specifically recommended for use in studies related to prostate cancer.

for DU 145 nuclear extractExtract Origin

Human Prostate (metastatic site: brain)

for DU 145 nuclear extractExtract Composition

DU 145 nuclear extract is supplied in Dilution Buffer (20 mM Hepes (pH 7.9), 100 mM KCl, 1 mM MgCl2, 20% glycerol, 0.5 mM PMSF and 0.5 mM DTT).

for DU 145 nuclear extractQuality Control

Extracts have been quality control tested by Western blot and the Electrophoretic Mobility Shift Assay (EMSA).

for DU 145 nuclear extractStorage

To ensure stability, extracts should be stored at -80°C.

We recommend aliquoting the extracts into single-use fractions and then storing them at -80°C. This eliminates repeated freeze/thaw cycles.

for DU 145 nuclear extractGuarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.


Technical Data Sheet

DU 145 nuclear extract